RADIOGRAPHIC EVALUATION OF THE EFFECT OF PORCINE SUBMUCOSAMEMBRANE GRAFT AND BIOACTIVE GLASS ON BONE FILLING IN RAT CALVARIA

Authors

  • Pedro Francisco Ribeiro Bonassoli
  • Fábio Bonamin dos Santos
  • Sônia Mara Luczyszyn
  • Vula Papalexiou
  • Sung Hyun Kim
  • Vinicius A. Tramontina

DOI:

https://doi.org/10.7213/aor.v7i3.23099

Keywords:

Bioactive glass, Porcine submucosa membrane, Bone repair

Abstract


Objectives: The aim of this study was to radiographically evaluate the filling of standardized bone defectsin rat calvaria treated with bioactive glass and with porcine submucosa membrane, alone or in combination,when compared to defects filled with clot. Materials and methods: Eighty male Wistar rats, weighing 250to 300 g, were divided into four groups, with trial period of two and eight weeks. Standardized bone woundswere surgically created in the calvaria measuring 6 mm in diameter and treated with bioactive glass, porcinesubmucosa membrane, combination of both or only clot. After two or eight weeks, the animals wereeuthanized and bone specimens were collected for evaluation with standard radiographs and digitized foranalysis with ImageJ image analyzer to compare the percentage of filling of the defects by measuring thevariations of levels of gray. Data were scored and analyzed statistically (ANOVA and Tukey HSD, p < 0.05).Results: The association of bioactive glass and submucosa membrane showed the best result of filling ofbone cavities, followed by the single use of bioactive glass. Membrane alone showed similar results withthe clot group. Conclusion: It was possible to conclude that the association of bioactive glass and porcinesubmucosa membrane could be good option for bone filling of bone defects.

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Published

2011-11-28

How to Cite

Bonassoli, P. F. R., Santos, F. B. dos, Luczyszyn, S. M., Papalexiou, V., Kim, S. H., & Tramontina, V. A. (2011). RADIOGRAPHIC EVALUATION OF THE EFFECT OF PORCINE SUBMUCOSAMEMBRANE GRAFT AND BIOACTIVE GLASS ON BONE FILLING IN RAT CALVARIA. Archives of Oral Research, 7(3). https://doi.org/10.7213/aor.v7i3.23099

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Articles