TERATOGENIC POTENTIAL OF A PESTICIDE TO INDUCE CLEFT PALATE IN RATS

Authors

  • Elisa Souza Camargo
  • Roberto Rocha
  • Robert Willer Farinazzo Vitral
  • Michelle Santos Vianna-Lara
  • Orlando Tanaka
  • Renato Kobler Pinto Sampaio

DOI:

https://doi.org/10.7213/aor.v2i5/6.23020

Keywords:

Pesticides, Methyl Parathion, Cleft palate, Rats.

Abstract

OBJECTIVES: The aim of this research was to evaluate the teratogenic potential of a pesticide to cause cleft palate in rats. MATHERIALS AND METHODS: Two groups of females were exposed to Folidol ® (methyl parathion) twice a day, Group 1 was exposed before gestation, and Group 2 during the gestational period. The offspring of females from both groups were submitted to macroscopic evaluation of the palate, using a Leica Stereo Microscope ZOOM 2.000, with 45x magnification. RESULTS: No presence of cleft palate was verified in the studied specimens. CONCLUSION: The studied pesticide did not induce cleft palate in rats fetuses, under the conditions of the present study.

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Published

2006-11-28

How to Cite

Camargo, E. S., Rocha, R., Vitral, R. W. F., Vianna-Lara, M. S., Tanaka, O., & Sampaio, R. K. P. (2006). TERATOGENIC POTENTIAL OF A PESTICIDE TO INDUCE CLEFT PALATE IN RATS. Archives of Oral Research, 2(5/6). https://doi.org/10.7213/aor.v2i5/6.23020

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Articles