Histomorphometrical analysis on the effects of two therapeutic ultrasound intensities on fracture healing in aged rats [I]
AbstractIntroduction: Experimental studies conducted in young animals show that therapeutic ultrasound (TUS) has been successfully used to shorten the healing time of bone fractures. However, they were not found in the literature, studies comparing the effect of different intensities of UST in aged animals. Objective: To test the efficacy of intensity 1.0 W/cm² and of 0.5 W/cm² in the consolidation of experimental fracture of the tibia from aged Wistar rats. Materials and methods: Three groups of 15 month old rats were submitted to a midshaft osteotomy of the tibia and then, the hind member was immobilized with a metal splint and plaster of Paris, wrapping the knee and ankle joint. One group (L), received ultrasound at 0.5 W/cm²; the other group (I), were exposed to ultrasound at 1.0 W/cm². One control group (C), did not receive the ultrasound. Fifteen animals (five from each group) were euthanatized at the end of the first week and fifteen (five from each group) at the end of the third week. The progress of the fracture healing was performed for each group by morphometric analysis of histological sections of the fracture region. Results and conclusion: The results showed that fractures treated with ultrasound at 1.0 W/cm2 healed significantly faster than did the fractures treated with ultrasound at 0.5 W/cm2 and the control.
How to Cite
The authors guarantee that the works submitted to this journal are original and were not prepared in violation of any third party rights, having obtained all the necessary authorizations to include complementary content, such as, but not restricted to, translations, illustrations, tables and citations, whose precise sources the author also undertakes to indicate. The authors also declare that the works do not contain defamatory statements that violate morals, good customs and/or that violate intellectual property rights.
When submitting your paper, the Copyright Assignment signed by all authors must be attached.