Efficacy of curcumin in treating palatal changes associated with reverse smoking

Autores

  • N. Vijayalaxmi
  • R. Sudhakara Reddy
  • T. Ramesh
  • N. Saimadhavi
  • R. Lavanya Reddy
  • L. A. Swapna

DOI:

https://doi.org/10.7213/aor.v8i1.23077

Palavras-chave:

Curcumin, Palatal changes, Reverse smoking

Resumo


Objectives: To evaluate the efficacy of curcumin reparation on the palatal changes associated with reverse smoking. Materials and methods: The study sample was divided into two groups with ten reverse smoking patients each. Group A patients were advised to use curcumin oral gel on an acrylic palatal plate whereas group B patients were instructed about the benefits of smoking cessation. Clinical and cytological smear examinations were performed at the first visit and at the end of the third visit. Data obtained was subjected to statistical analysis. Results: Evident improvement with reduction in size and severity of the clinical lesion was observed among the study group at both first and third visits (p < 0.001, significant). However, the cytological appearances remained the same in all the cases, except for three cases from the study group,which demonstrated a transition from moderate dysplastic features to milder dysplastic features (p = 0.28, not significant). Conclusion: Due to its diverse array of molecular targets, curcumin affords great potentialas a therapeutic agent for precancerous and cancerous conditions. Results from our pilot study have clearlyshown that curcumin is effective in the treatment of the palatal changes associated with reverse smoking.

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Publicado

2012-11-28

Como Citar

Vijayalaxmi, N., Reddy, R. S., Ramesh, T., Saimadhavi, N., Reddy, R. L., & Swapna, L. A. (2012). Efficacy of curcumin in treating palatal changes associated with reverse smoking. Archives of Oral Research, 8(1). https://doi.org/10.7213/aor.v8i1.23077

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